Cancer Therapy Selection
Category: ARTICLES, Info & Tips, Health & Beauty
Choosing
a cancer drug is not easy, a lot of factors to consider such as type of
cancer, and radiosensitivitas Kemosensitivitas cancer, body immunity
and the ability of patients to receive the treatment that we give, side
effects of therapy we give.Cancer Types For the purposes of the administration of chemotherapy, the cancer is divided into 2 types:1.KANKER Hemopoitik and limfopoitik.Limfopoitik hemopoitik cancer and is generally a systemic cancer. Included in this type of cancer is cancer of the blood (leukemia), malignant lymphoma and bone marrow (myeloma). The main therapy is kenker hematology chemotherapy, surgery and radiotherapy while as an adjuvant.2.Kanker solid (solid).Solid cancers can be local, and may spread to regional or systemic to other organs. In this type of cancer, including cancers beyond hematology. Primary
therapy of cancer are surgery and or radiotherapy, whereas chemotherapy
was only given as an adjuvant at an advanced stage.Sensitivity Cancer tumor sensitivity to anti-cancer drugs are not the same, so it is divided into 3 types:1. Sensitive
chemosensitive: - leukemia - malignant lymphoma - myeloma -
choriocharsinoma - radiosensitive testicular cancer: tumors that can be
destroyed with a dose of 3500-6000 rads in 3-4 weeks - Malignant
Lymphoma - Myeloma - Retinoblastoma - Seminoma - Basalioma - T1
laryngeal cancer2. Responsive
Kemoresponsif: - Small Tumors - Tumors that grow quickly - tumor cell
differentiation ugly Radioresponsif - cancer is a size medium, T2-T3 and
can be destroyed with a dose of 6000-8000 rads in 3-4 weeks3. Resistant
Kemoresisten: - Tumor great - slow-growing cancer - Cancer cells are
well differentiated Example: brain cancer, fibrosarcoma, malignant
melanoma radioresistant tumors can only be destroyed with a dose of
8,000 rads. Example: Malignant melanoma, adenocarcinoma, brain cancer, soft tissue sarcoma.Radiosensitivitas tumors depends on many factors, among others:a. Type of tumor histologyb. The degree of cell differentiationc. Large tumord. Tumor vascularizatione. Location
of tumor topography Several types of drugs and circumstances that may
increase the sensitivity of radiotherapy: Oxygenation, Hipertermi,
levamisole, some sitostatika. The
sensitivity of cancers to chemotherapy usually there from the beginning
and can also arise in the course of cancer treatment.Resistance Against Chemotherapy Resistance to chemotherapy can occur due to the pharmacokinetics of the drug such as:a. Changes
in absorption - variability in gastrointestinal absorption of drugs -
The gastointestinal disease - Not taking medication as it should
(non-compliance) - drug formulations that do not fitb. Distribution
changes - Changes in drug binding to serum proteins - Changes in the
distribution because other drugs that bind to serum proteinsc. Metabolic
changes - changes that hold detoxification enzymes - Liver disease -
There are other drugs that participated - Reducing drug conjugates with
age d. Reduced excretion - liver disease - kidney disease by Dr. Heru Noviat ~ Herdata SpA.
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Category: ARTICLES, Info & Tips, Health & Beauty
http://ebookfkunsyiah.wordpress.com/2008/09/04/pemilihan-terapi-kanker/