Cancer Therapy Selection

Cancer Therapy Selection 


Category: ARTICLES, Info & Tips, Health & Beauty

Choosing a cancer drug is not easy, a lot of factors to consider such as type of cancer, and radiosensitivitas Kemosensitivitas cancer, body immunity and the ability of patients to receive the treatment that we give, side effects of therapy we give.Cancer Types For the purposes of the administration of chemotherapy, the cancer is divided into 2 types:1.KANKER Hemopoitik and limfopoitik.Limfopoitik hemopoitik cancer and is generally a systemic cancer. Included in this type of cancer is cancer of the blood (leukemia), malignant lymphoma and bone marrow (myeloma). The main therapy is kenker hematology chemotherapy, surgery and radiotherapy while as an adjuvant.2.Kanker solid (solid).Solid cancers can be local, and may spread to regional or systemic to other organs. In this type of cancer, including cancers beyond hematology. Primary therapy of cancer are surgery and or radiotherapy, whereas chemotherapy was only given as an adjuvant at an advanced stage.Sensitivity Cancer tumor sensitivity to anti-cancer drugs are not the same, so it is divided into 3 types:1. Sensitive chemosensitive: - leukemia - malignant lymphoma - myeloma - choriocharsinoma - radiosensitive testicular cancer: tumors that can be destroyed with a dose of 3500-6000 rads in 3-4 weeks - Malignant Lymphoma - Myeloma - Retinoblastoma - Seminoma - Basalioma - T1 laryngeal cancer2. Responsive Kemoresponsif: - Small Tumors - Tumors that grow quickly - tumor cell differentiation ugly Radioresponsif - cancer is a size medium, T2-T3 and can be destroyed with a dose of 6000-8000 rads in 3-4 weeks3. Resistant Kemoresisten: - Tumor great - slow-growing cancer - Cancer cells are well differentiated Example: brain cancer, fibrosarcoma, malignant melanoma radioresistant tumors can only be destroyed with a dose of 8,000 rads. Example: Malignant melanoma, adenocarcinoma, brain cancer, soft tissue sarcoma.Radiosensitivitas tumors depends on many factors, among others:a. Type of tumor histologyb. The degree of cell differentiationc. Large tumord. Tumor vascularizatione. Location of tumor topography Several types of drugs and circumstances that may increase the sensitivity of radiotherapy: Oxygenation, Hipertermi, levamisole, some sitostatika. The sensitivity of cancers to chemotherapy usually there from the beginning and can also arise in the course of cancer treatment.Resistance Against Chemotherapy Resistance to chemotherapy can occur due to the pharmacokinetics of the drug such as:a. Changes in absorption - variability in gastrointestinal absorption of drugs - The gastointestinal disease - Not taking medication as it should (non-compliance) - drug formulations that do not fitb. Distribution changes - Changes in drug binding to serum proteins - Changes in the distribution because other drugs that bind to serum proteinsc. Metabolic changes - changes that hold detoxification enzymes - Liver disease - There are other drugs that participated - Reducing drug conjugates with age d. Reduced excretion - liver disease - kidney disease by Dr. Heru Noviat ~ Herdata SpA.

http://ebookfkunsyiah.wordpress.com/2008/09/04/pemilihan-terapi-kanker/

Know the 10 Signs of Prostate Cancer Early!

Know the 10 Signs of Prostate Cancer Early ! 


Category: ARTICLES, Info & Tips, Health & Beauty

Prostate cancer is one of the 10 most common diseases that afflict man. Unfortunately, men often are not aware of him until the disease is spread and more difficult diterapi.Bisa so this is a result of too many symptoms. At least, there is a way to recognize the symptoms of prostate cancer. Let's look at the following signs:1. Difficult urinationIt can be a feeling of wanting to urinate but nothing comes out, stop when you're urinating, there is a feeling still want or need to frequently urinate into the toilet to urinate due to the release of a little - a little. This phenomenon is due to enlargement of the prostate gland is around the urinary tract due to a tumor in it so interfere with the process of urination. The prostate gland will be greater with increasing age. Therefore, check with your doctor to distinguish whether only an enlarged prostate or cancer.2. Pain during urinationThis problem is also due to prostate tumor pressing urinary tract. However, pain can also be a symptom of prostate infection called prostatitis. It could also be a sign of prostate hyperplasia is not cancer.3. Bleeding during urinationThese symptoms are rare, but should not be ignored. Immediately see a doctor even though blood ejected only a few, vague - vague or just pink. Sometimes urinary tract infections can also cause these symptoms.4. Hard erection or sustain an erectionProstate tumors may cause blood flow to the penis which should increase when the erection becomes blocked so hard erection. It could also lead to can not ejaculate after erection. But again, an enlarged prostate may cause these symptoms.5. Blood in semenThese symptoms, such as blood in the urine, may arise not so clear. Blood is not in large quantities, and cause the color changed to pink. Still worth a watch6. Difficult Toilet (BAB) and other gastrointestinal problemsThe prostate gland is located below the bladder and in front of the rectum. Consequently, when there will be disrupted gastrointestinal tumors. But remember, it is difficult CHAPTER Persistent can also cause enlarged prostate gland due to pressure on a continuous basis. Difficult bowel and gastrointestinal disorders may also indicate colon cancer.7. Continuous pain in the lower back, pelvis or upper thighs inFrequently, prostate cancer spread in these regions, ie at the lower back, pelvis and hip pain that is difficult to explain in this section could be a sign of disturbance8. Frequent urination at nightIf you often wake up at night more than once just to urinate, check immediately to the doctor.9. Urine dripping or not strong enoughThese symptoms are similar to urinary incontinence (bedwetting). Urine can not be held up and drips slowly out. Or if it was not strong enough flow out.10. Age greater than 50 and have risk factorsSince no symptoms then men who have risk factors should be screened regularly. These risk factors include a family member with cancer, especially if it is the father, obesity / overweight and smoking is a risk factor for prostate cancer.

by dr. Intan Airlina Febiliawantikompas.com

Beware Triglyceride Threat

Beware Triglyceride Threat   


Category: ARTICLES, Info & Tips, Health & Beauty

FOR those who are constantly monitoring the levels of fat in the blood, triglycerides said probably not a term foreign to the ear. Triglycerides are the main fat in the body that is closely associated with cholesterol, both of which have a relationship that can not be separated in the process of metabolism.Some recent research indicates, this type of fat that one should be wary because it can become a more serious threat to health. Reflecting the research, the experts stressed the importance of the handling of triglycerides better.A study earlier this week said the phenomenon of people with high triglyceride levels in the United States is becoming increasingly apparent. The percentage of people with high trigeliserida increasing in the last three decades and seems to be triggered by the rampant cases of obesity.In another study, Danish scientists reported that blood tests without fasting showed a strong link between high triglyceride levels and rsiko stroke due to blood clotting.Triglycerides are blood fats that are specifically located on the second tier of low-density lipoprotein or LDL, is known as "bad" cholesterol because of its role in triggering heart attacks and strokes. Cholesterol-lowering drugs known as 'statins' it can reduce LDL, but the drug is often not able to lower triglycerides - blood fats obtained from food consumed and fat in the body.Triglycerides itself is an independent risk factor for heart disease, the leading cause of death in the U.S.. Triglycerides and other lipids are typically measured after the fasting for eight to 12 hours.Danish study published the Journal of the American Medical Association, Borge Noerdestgaard of Copenhagen University Hospital analyzed fasting triglyceride levels without the need to see how well they can predict the risk of stroke.For example, people aged 55 years or more with the highest triglyceride levels-above 443 milligrams per deciliter-had a 17 percent risk of stroke within 10 years. While most people with low triglyceride levels, 89 percent per deciliter, has a 3 percent risk of having a stroke."People are not fasting triglycerides may be even better than the fasting triglycerides in predicting risk," Nordestgaard said.He said the examination without fasting much more reassuring for patients, a factor that may facilitate the examination for many people.Dipresenrasikan research at the American Heart Association in New Orleans, found that the trend of elevated triglyceride levels in the U.S. are becoming apparent. The results of government health survey for 30 years found that while LDL levels have dropped, the percentage of adults with high triglyceride levels rise many fold."When LDL is absorbed by the use of statins, triglycerides emerged as a new risk factor for blood lipids," said Dr. Jerome Cohen of St.. Louis University School of Medicine in Missouri.He said the study shows a dramatic increase in the number of obese Americans may help explain the increases.Meanwhile, Dr. Irene Katzan of the Cleveland Clinic in Ohio said the results of the research and the other reflecting the increased attention to the issue of control triglycerides. "Finally fats (triglycerides) it gets the proper attention," he said.

adapted from www.kompas.com
 Sources: http://aldiperdana.web.ugm.ac.id/trigliserida.html